USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

USC-OGP 2-DE database  Search by                Maps             Select Remote Interfaces [All Interfaces] SWISS-2DPAGE World-2DPAGE Portal World-2DPAGE Repository Exclude local DBs has only effect if a remote interface is selected

Searching in 'USC-OGP 2-DE database' for entry matching: Q15833 USC-OGP 2-DE database:  Q15833 Q15833 General information about the entry View entry in simple text format Entry name STXB2_HUMAN Primary accession number Q15833 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Syntaxin-binding protein 2; AltName: Full=Protein unc-18 homolog 2; Short=Unc18-2; AltName: Full=Protein unc-18 homolog B; Short=Unc-18B;. Gene name Name=STXBP2 Synonyms=UNC18B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein PLATELET_4-7 {PLATELET 4-7} Homo sapiens (Human)   map experimental info   PLATELET_4-7 MAP LOCATIONS: SPOT OGP-0316: pI=6.01; Mw=67425 PLATELET_5-6 {PLATELET 5-6} Homo sapiens (Human)   map experimental info   PLATELET_5-6 MAP LOCATIONS: SPOT OGP-0641: pI=5.93; Mw=68069 Cross-references UniProtKB/Swiss-Prot Q15833; STXB2_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name STXB2_HUMAN Primary accession number Q15833 Secondary accession number(s) B4E175 E7EQD5 Q9BU65 Sequence was last modified on  November 30, 2010 (version 2) Annotations were last modified on  March 15, 2017 (version 143) Name and origin of the protein Description RecName: Full=Syntaxin-binding protein 2; AltName: Full=Protein unc-18 homolog 2; Short=Unc18-2; AltName: Full=Protein unc-18 homolog B; Short=Unc-18B; Gene name Name=STXBP2 Synonyms=UNC18B Encoded on Name=STXBP2; Synonyms=UNC18B Keywords 3D-structure; Alternative splicing; Complete proteome; Disease mutation; Exocytosis; Polymorphism; Protein transport; Reference proteome; Transport. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL U63533; AAC50762.1; -; mRNA EMBL BT006915; AAP35561.1; -; mRNA EMBL AK303701; BAG64687.1; -; mRNA EMBL AC008763; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL CH471139; EAW69018.1; -; Genomic_DNA EMBL BC002869; AAH02869.1; -; mRNA CCDS CCDS12181.1; -. [Q15833-1]; . CCDS CCDS45948.1; -. [Q15833-2]; . CCDS CCDS62522.1; -. [Q15833-3]; . RefSeq NP_001120868.1; NM_001127396.2. [Q15833-2]; . RefSeq NP_001258963.1; NM_001272034.1. [Q15833-3]; . RefSeq NP_008880.2; NM_006949.3. [Q15833-1]; . UniGene Hs.515104; -; . PDB 4CCA; X-ray; 2.60 A; A=1-593 PDBsum 4CCA; -; . ProteinModelPortal Q15833; -; . SMR Q15833; -; . BioGrid 112682; 21; . IntAct Q15833; 6; . MINT MINT-4718353; -; . STRING 9606.ENSP00000221283; -; . iPTMnet Q15833; -; . PhosphoSitePlus Q15833; -; . DMDM 313104015; -; . OGP Q15833; -; . EPD Q15833; -; . MaxQB Q15833; -; . PaxDb Q15833; -; . PeptideAtlas Q15833; -; . PRIDE Q15833; -; . DNASU 6813; -; . Ensembl ENST00000221283; ENSP00000221283; ENSG00000076944. [Q15833-1]; . Ensembl ENST00000414284; ENSP00000409471; ENSG00000076944. [Q15833-2]; . Ensembl ENST00000441779; ENSP00000413606; ENSG00000076944. [Q15833-3]; . GeneID 6813; -; . KEGG hsa:6813; -; . UCSC uc002mha.6; human. [Q15833-1]; . CTD 6813; -; . DisGeNET 6813; -; . GeneCards STXBP2; -; . GeneReviews STXBP2; -; . H-InvDB HIX0021726; -; . HGNC HGNC:11445; STXBP2; . HPA HPA015564; -; . HPA HPA063868; -; . MalaCards STXBP2; -; . MIM 601717; gene; . MIM 613101; phenotype; . neXtProt NX_Q15833; -; . OpenTargets ENSG00000076944; -; . Orphanet 540; Familial hemophagocytic lymphohistiocytosis; . PharmGKB PA36242; -; . eggNOG KOG1300; Eukaryota; . eggNOG COG5158; LUCA; . GeneTree ENSGT00390000005206; -; . HOGENOM HOG000232146; -; . HOVERGEN HBG052710; -; . InParanoid Q15833; -; . KO K15300; -; . OMA PRERMEP; -; . OrthoDB EOG091G0WUI; -; . PhylomeDB Q15833; -; . TreeFam TF313242; -; . Reactome R-HSA-114608; Platelet degranulation; . SIGNOR Q15833; -; . ChiTaRS STXBP2; human; . GeneWiki Syntaxin_binding_protein_2; -; . GenomeRNAi 6813; -; . PRO PR:Q15833; -; . Proteomes UP000005640; Chromosome 19; . Bgee ENSG00000076944; -; . CleanEx HS_STXBP2; -; . ExpressionAtlas Q15833; baseline and differential; . Genevisible Q15833; HS; . GO GO:0016324; C:apical plasma membrane; IEA:Ensembl; . GO GO:0042582; C:azurophil granule; IDA:UniProtKB; . GO GO:0044194; C:cytolytic granule; IDA:UniProtKB; . GO GO:0005829; C:cytosol; IDA:UniProtKB; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0005886; C:plasma membrane; IDA:UniProtKB; . GO GO:0042581; C:specific granule; IDA:UniProtKB; . GO GO:0070820; C:tertiary granule; IDA:UniProtKB; . GO GO:0042589; C:zymogen granule membrane; IEA:Ensembl; . GO GO:0030348; F:syntaxin-3 binding; IPI:UniProtKB; . GO GO:0001909; P:leukocyte mediated cytotoxicity; IMP:UniProtKB; . GO GO:0043312; P:neutrophil degranulation; IEP:UniProtKB; . GO GO:0002576; P:platelet degranulation; TAS:Reactome; . GO GO:0015031; P:protein transport; IEA:UniProtKB-KW; . GO GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB; . GO GO:0006904; P:vesicle docking involved in exocytosis; IEA:InterPro; . Gene3D 3.40.50.1910; -; 2; . InterPro IPR027482; Sec-1-like_dom2; . InterPro IPR001619; Sec1-like; . PANTHER PTHR11679; PTHR11679; 1; . Pfam PF00995; Sec1; 1; . PIRSF PIRSF005715; VPS45_Sec1; 1; . SUPFAM SSF56815; SSF56815; 1; .

Gateways to other related servers

• The World-2DPAGE Constellation - Entry point to the world-wide 2-DPAGE resources.
• World-2DPAGE Repository - A public repository for gel-based proteomics data linked to protein identification published in the literature.
• World-2DPAGE Portal - A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
• SWISS-2DPAGE - The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
• ExPASy - The resources web server of the Swiss Institute of Bioinformatics

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